Abstract

Candidiasis is the most common fungal infection complicating the course of the patients with hematologic malignancies. Although widespread organ involvement is characteristic of systemic candidiasis, report of skin involvement is rare. A 22-year-old man with acute lymphocytic leukemia showed fever and painful erythematous maculopapular eruptions on the whole body after combination chemotherapy of mitoxanthrone, cytosine arabinoside and etoposide. Histopathologic sections from the skin lesions showed sparse perivascular mononuclear cell infiltration in the dermis, and many blastospores and pseudohyphae within the dermis and subcutis. The patient died in spite of treatment with intravenous amphotericin B and oral flucytosine. 

Keywords

Skin involvement Systemic candidiasis

KJMM 1998 June;3(1):67-72(6). Epub 2016 February 25
Copyright © 1998 by Korean Journal of Medical Mycology

Language

Korean/English

Author

Jin Young Park; Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Dong Won Lee; Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Jun Young Lee; Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Baik Kee Cho; Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea

Corresponding

Jin Young Park, Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Publication history

Acknowledgements

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Jin Young Park

Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea

Dong Won Lee

Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea

Jun Young Lee

Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea

Baik Kee Cho

Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea

Since epub date 2016 February 25