Cutaneous Abscess Caused by Paecilomyces lilacinus in a Renal Transplant Patient
Abstract
Paecilomyces lilacinus is an ubiquitous saprophytic fungus and very rarely pathogenic to the human. Although it has been reported to cause endophthalmitis, orbital cellulitis, prosthetic valve endocarditis, and pulmonary infection, cutaneous infection caused by Paecilomyces lilacinus has been rarely reported. A 46-year-old Korean man had asymptomatic slowly growing multiple cutaneous nodules on the left arm and wrist for 8 months. He received a renal transplantation in 1991 because of end-stage renal disease. Postoperatively, he has taken cyclosporin and deflazacort for immunosuppression. Physical examination revealed that the lesions were discrete or confluent, firm, elevated, well-defined fluctuating nodules. Histologic section showed multiple well-encapsulated intradermal abscesses with some foci of chronic granulomatous changes composed of lymphocytes, histiocytes and giant cells. PAS positive fungal hyphae and spores were also found. On the Sabouraud's dextrose agar media, the organism grew rapidly to form velvety lilac-colored colonies with shallow radiating furrows. Slide culture showed brush-like conidiophores ending in flask-shaped phialides carrying chain of conidia. Because of the poor response to the oral antifungal drug for 2 months, all the lesions were completely excised.
Keywords
Cutaneous abscess Paecilomyces lilacinus Renal transplant
KJMM
1998 December;3(2):185-189(5). Epub 2016 February 24
Copyright © 1998 by Korean Journal of Medical Mycology
Language
Korean/English
Author
Sang Boo Shin; Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Hye Nam Lee; Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Sung Wook Kim; Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Gun Su Park; Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Baik Kee Cho; Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Hee Jung Kim; Department of Clinical Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Corresponding
Sang Boo Shin, Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Publication history
Acknowledgements
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Sang Boo Shin
Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Hye Nam Lee
Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Sung Wook Kim
Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Gun Su Park
Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Baik Kee Cho
Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Hee Jung Kim
Department of Clinical Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea
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