Abstract

For the thirty years till 1990, griseofulvin and ketoconazole had been the only available oral antifungal agents. These drugs have not been used widely due to their many drawbacks such as low therapeutic efficacy, long duration of treatment and serious side effects. Nowadays, the newer oral antifungal agents, itraconazole, terbinafine, and fluconazole are used widely because of the improved therapeutic efficacy and an acceptable adverse effects profile. But, there is a spectrum of adverse effects and drug interactions for the these newer oral antifungal agents. In terms of the safety of these newer oral antifungal agents, I think that a little concerns of the dermatologists can reduce the possible adverse effects and the various drug interactions.

Keywords

Safety Antifungal agents

KJMM 2001 September;6(3):129-134(6). Epub 2016 February 22
Copyright © 2001 by Korean Journal of Medical Mycology

Language

Korean/English

Author

Kyung Sool Kwon; Department of Dermatology, College of Medicine, Pusan National University, Pusan, Korea

Corresponding

Kyung Sool Kwon, Department of Dermatology, College of Medicine, Pusan National University, Pusan, Korea. Tel: (051) 240-7337, Fax: (051) 245-9467, e-mail: kwonks@pusan.ac.kr

Publication history

Acknowledgements

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Kyung Sool Kwon

Department of Dermatology, College of Medicine, Pusan National University, Pusan, Korea

Since epub date 2016 February 22