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A Case of Cutaneous Cryptococcosis Resembling Verrucous Granuloma

Woo Gil Chung,Junsu Park,Yoon Kee Park,Kwang Hoon Lee
Epub 2016 February 22

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Abstract



We report a case of cutaneous cryptococcosis resembling verrucous granuloma on the lower lip in a 18-year-old female. She presented with a 3×1.5 cm sized painful verrucous granuloma with white, yellowish crust on the lower lip for 1 year. She had gotten many shunt operations for unexplained hydrocephalus. Histopathological examination showed numerous encapsulated round spores, epithelioid cells and giant cells in the dermis. A tissue culture on Sabouraud's dextrose agar without cycloheximide showed whitish creamy colonies. The organism was identified as Cryptococcus neoformans. The lesion disappeared with the treatment of oral itraconazole (100 mg/day) for 12 weeks.



Keywords


Cryptococcosis Itraconazole




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