Abstract

Background: Clinical success rate is determined by patients compliance which depends on treatment method and period. Retrospective study to clinical success rate may give the information to promote compliance with oral medications for onychomycosis.

Objective: The purpose of this study was to evaluate clinical success rate in the different treatment group.

Method: For the retrospective study, 618 patients diagnosed clinically and mycologically as having onychomycosis were evaluated for the cure rate and drop-out rate.

Results: The drop-out rate was 31.5% in itraconazole monthly pulse group, 74.3% in itraconazole daily continuous group, 77.5% in terbinafine daily continuous group and 97.8% in fluconazole weekly pulse group. Therefore the success rate was 68.5% in itraconazole monthly pulse group, 25.7% in itraconazole daily continuous group, 22.5% in terbinafine daily continuous group and 2.2% in fluconazole weekly pulse group. The drop-out rate was high in the first period of treatment schedule in most of treatment groups except itraconazole monthly pulse and daily continuous groups.

Conclusion: We concluded that the treatment duration and method are the critical factor to treat tonail onychomycosis relating in determining patients' preference for treatment schedules.

Keywords

Onychomycosis Patient compliance Clinical success rate

KJMM 2002 September;7(3):149-154(6). Epub 2016 February 20
Copyright © 2002 by Korean Journal of Medical Mycology

Language

Korean/English

Author

Yang Won Lee; Department of Dermatology, College of Medicine, Konkuk University, Seoul, Korea
Seong Tae Jeong; Department of Dermatology, College of Medicine, Konkuk University, Seoul, Korea
Kyu Joong Ahn; Department of Dermatology, College of Medicine, Konkuk University, Seoul, Korea

Corresponding

Kyu Joong Ahn, Department of Dermatology, College of Medicine, Konkuk University, Seoul, Korea. Tel: (02) 450-9679, Fax: (02) 450-9547, e-mail: kjahn@konkuk.ac.kr

Publication history

Acknowledgements

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Yang Won Lee

Department of Dermatology, College of Medicine, Konkuk University, Seoul, Korea

Seong Tae Jeong

Department of Dermatology, College of Medicine, Konkuk University, Seoul, Korea

Kyu Joong Ahn

Department of Dermatology, College of Medicine, Konkuk University, Seoul, Korea

Since epub date 2016 February 20