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Familial Chronic Mucocutaneous Candidiasis

Kwang Hyun Choi,Hei Sung Kim,Hyung Ok Kim,Young Min Park
Epub 2016 February 18

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Abstract



Chronic mucocutaneous candidiasis (CMCC) is a complex group of disorder characterized by chronic and recurrent candida infections of the skin, nail and oropharynx. The classification of CMCC varies but is commonly based on the clinical feature, existence of an endocrinopathy, and the pattern of inheritance, which can be either autosomal

dominant or recessive. We herein report a rare case of familial CMCC. A family of a 42-year-old woman and her 17- 

and 12-year-old daughters commonly presented with a recurrent whitish plaque in the oral cavity for several years,

and the mother and her 9-year-old son also had presented with dystrophic nails. They had no evidence of concomitant immunodeficiency or endocrinopathy. Candida albicans was commonly isolated from the oral lesion of the mother and two daughters. They were successfully managed with intermittent oral antifungal treatment.



Keywords


Familial Chronic mucocutaneous candidiasis




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