A Case of Majocchi's Granuloma of the Face of an Immunocompetent Patient Caused by Trichophyton rubrum
Abstract
Majocchi's granuloma is well recognized but uncommon infection of dermal and subcutaneous tissue by fungal organisms usually limited to the superficial epidermis. The organism most commonly associated with Majocchi's granuloma is Trichophyton(T.) rubrum, however, other dermatophytes may be the causative agent. A 44-year-old male patient presented with a 6 month history of two well defined erythematous nodular plaques on his right jaw and preauricular area. Histopathologic findings were consistent with the Majocchi's granuloma, showing perifolliculitis and granulomatous inflammation in the dermis. Many fungal elements were noted within the giant cells of the perifollicular dermis of PAS stained section. T. rubrum was cultured from the biopsy specimen and confirmed by slide culture. After
10 weeks of terbinafine (Lamisil®) therapy (250 mg/day), lesions were cleared with mild erythematous patches and atrophic scars.
Keywords
Majocchi's granuloma Trichophyton rubrum
KJMM
2010 June;15(2):77-82(6). Epub 2016 February 18
Copyright © 2010 by Korean Journal of Medical Mycology
Language
Korean/English
Author
Hyo Sang Ahn; Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Jung Eun Kim; Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Hyun Jeong Park; Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Baik Kee Cho; Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Moo Kyu Suh; Department of Dermatology, College of Medicine, Dongguk University, Gyeongju, Korea
Corresponding
Baik Kee Cho, Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea. Tel: (02) 3779-1230, Fax: (02) 783-7604, e-mail: bkcho@catholic.ac.kr
Publication history
Received 8 December 2009;
Revised 10 March 2010;
Accepted 12 March 2010.
Acknowledgements
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Hyo Sang Ahn
Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Jung Eun Kim
Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Hyun Jeong Park
Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Baik Kee Cho
Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Moo Kyu Suh
Department of Dermatology, College of Medicine, Dongguk University, Gyeongju, Korea
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Since epub date 2016 February 18