Abstract

Fusarium(F.) species are hyalohyphomycetes isolated from plants, soil and air. Fusarium species can cause disseminated infections with involvement of multiple organs and numerous skin lesions in immunocompromised patients. And they can also cause local skin infections of trauma site. We report a case of localized skin infection by F. oxysporum in a 63-year-old immunocompetent woman. She presented with multiple, mild pruritic, 1.5 × 1.5 cm-sized, erythematous maculopapules on the left cheek after cosmetic procedure 4 months ago. Histopathologically, suppurative granulomatous inflammation, fungal elements were observed in dermis. Fungal culture on Sabouraud's dextrose agar showed rapid growing, whitish, cottony colonies at 25℃ for 1 week. Numerous fusoid macroconidia were observed in slide culture by light microscopy. The nucleotide sequences of the internal transcribed spacer (ITS) region of clinical sample identical to that of F. oxysporum CID 220 strain (GenBank accession number HQ829117.1). The patient had been treated with itraconazole for 6 months. The skin lesion was improved. There was no recurrence 6 months after treatment.

Keywords

Fusarium oxysporum Localized skin infection

KJMM 2013 September;18(3):70-75(6). Epub 2016 February 17
Copyright © 2013 by Korean Journal of Medical Mycology

Language

Korean/English

Author

Myung Hoon Lee; Departments of Dermatology, College of Medicine, Dongguk University, Gyeongju, Korea
Ji Young Yoo; Departments of Dermatology, College of Medicine, Dongguk University, Gyeongju, Korea
You Bum Song; Departments of Dermatology, College of Medicine, Dongguk University, Gyeongju, Korea
Moo Kyu Suh; Departments of Dermatology, College of Medicine, Dongguk University, Gyeongju, Korea
Gyoung Yim Ha; Departments of Laboratory Medicine, ollege of Medicine, Dongguk University, Gyeongju, Korea
Jong Im Lee; Departments of Pathology, College of Medicine, Dongguk University, Gyeongju, Korea
Hyo Jin Lee; Department of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea

Corresponding

Moo Kyu Suh, Departments of Dermatology, College of Medicine, Dongguk University, Gyeongju, Korea. Tel: +82-54-770-8268, Fax: +82-54-773-1581, e-mail: smg@dongguk.ac.kr

Publication history

Received 16 July 2013; Revised 13 September 2013; Accepted 13 September 2013.

Acknowledgements

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Myung Hoon Lee

Departments of Dermatology, College of Medicine, Dongguk University, Gyeongju, Korea

Ji Young Yoo

Departments of Dermatology, College of Medicine, Dongguk University, Gyeongju, Korea

You Bum Song

Departments of Dermatology, College of Medicine, Dongguk University, Gyeongju, Korea

Moo Kyu Suh

Departments of Dermatology, College of Medicine, Dongguk University, Gyeongju, Korea

Gyoung Yim Ha

Departments of Laboratory Medicine, ollege of Medicine, Dongguk University, Gyeongju, Korea

Jong Im Lee

Departments of Pathology, College of Medicine, Dongguk University, Gyeongju, Korea

Hyo Jin Lee

Department of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea

Since epub date 2016 February 17