A Case of Skin Infection due to Scedosporium apiospermum Treated with Voriconazole
Abstract
Scedosporium(S.) apiospermum has been isolated from polluted water, soil, sewage and potted plants in a hospital with low virulence. The localized skin infection due to S. apiospermum is rare and usually results from traumatic implantation of contaminated material due to a penetrating injury. We report a case of skin infection due to S. apiospermum in a 78-year-old female. She had multiple nodules, pustules and exudative ulcerative lesions at the right forearm. Cultured isolation for definitive diagnosis showed typical S. apiospermum. Treatment was started with itraconazole effectively, but skin lesions were recurred after 4 months, and then cured with voriconazole with no recurrence.
Keywords
Scedosporium apiospermum Skin infection Itraconazole Voriconazole
KJMM
2008 December;13(4):187-191(5). Epub 2016 February 18
Copyright © 2008 by Korean Journal of Medical Mycology
Language
Korean/English
Author
Yong Geun Jeong; Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Republic of Korea
In Gyu Bae; Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Republic of Korea
Min Hee Lim; Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Republic of Korea
Jae Hee Kim; Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Republic of Korea
Min Kyung Gang; Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Republic of Korea
Sun joo Kim; Department of Laboratory Medicine; Gyeongsang Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju, Republic of Korea
Sang Taek Heo; Department of Gyeongsang Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju, Republic of Korea
Corresponding
Sang Taek Heo, Department of Gyeongsang Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju, Republic of Korea. Tel: (055) 750-8874, Fax: (055) 755-9078, e-mail: cadevar@yahoo.co.kr
Publication history
Acknowledgements
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Yong Geun Jeong
Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Republic of Korea
In Gyu Bae
Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Republic of Korea
Min Hee Lim
Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Republic of Korea
Jae Hee Kim
Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Republic of Korea
Min Kyung Gang
Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, Republic of Korea
Sun joo Kim
Department of Laboratory Medicine; Gyeongsang Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju, Republic of Korea
Sang Taek Heo
Department of Gyeongsang Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju, Republic of Korea
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