Abstract

Paecilomyces lilacinus is an ubiquitous saprophytic fungus and very rarely pathogenic to the human. Although it has been reported to cause endophthalmitis, orbital cellulitis, prosthetic valve endocarditis, and pulmonary infection, cutaneous infection caused by Paecilomyces lilacinus has been rarely reported. A 46-year-old Korean man had asymptomatic slowly growing multiple cutaneous nodules on the left arm and wrist for 8 months. He received a renal transplantation in 1991 because of end-stage renal disease. Postoperatively, he has taken cyclosporin and deflazacort for immunosuppression. Physical examination revealed that the lesions were discrete or confluent, firm, elevated, well-defined fluctuating nodules. Histologic section showed multiple well-encapsulated intradermal abscesses with some foci of chronic granulomatous changes composed of lymphocytes, histiocytes and giant cells. PAS positive fungal hyphae and spores were also found. On the Sabouraud's dextrose agar media, the organism grew rapidly to form velvety lilac-colored colonies with shallow radiating furrows. Slide culture showed brush-like conidiophores ending in flask-shaped phialides carrying chain of conidia. Because of the poor response to the oral antifungal drug for 2 months, all the lesions were completely excised. 

Keywords

Cutaneous abscess Paecilomyces lilacinus Renal transplant

KJMM 1998 December;3(2):185-189(5). Epub 2016 February 24
Copyright © 1998 by Korean Journal of Medical Mycology

Language

Korean/English

Author

Sang Boo Shin; Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Hye Nam Lee; Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Sung Wook Kim; Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Gun Su Park; Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Baik Kee Cho; Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea
Hee Jung Kim; Department of Clinical Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea

Corresponding

Sang Boo Shin, Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Publication history

Acknowledgements

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Sang Boo Shin

Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea

Hye Nam Lee

Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea

Sung Wook Kim

Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea

Gun Su Park

Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea

Baik Kee Cho

Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea

Hee Jung Kim

Department of Clinical Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea

Since epub date 2016 February 24