Abstract

Phialemonium and Myrothecium species are rare agents of human deep mycosis infection and those have been increasingly documented as emerging agents of opportunistic infection in immunocompromised patients. We discribed a 69-year-old Korean male, previously diagnosed as lung cancer, presented with 2×2 cm sized normal skin to erythematous nodules on the both lower legs for 10 years. Biopsy specimen showed brownish septated hyphae in the dermis and subcutaneous tissue from the left lower leg and colorless spores from the right leg (H&E). Each identifications were confirmed by polymerase chain reaction of ITS2 using universal fungal primers as Phialemonium dimorphosporum on the left lower leg and Myrothecium species on the right lower leg. The patient was treated with surgical excision and fluconazole.

Keywords

Lung cancer Cutaneous deep mycosis Phialemonium dimorphosporum Myrothecium species ITS2

KJMM 2005 December;10(4):166-172(7). Epub 2016 February 20
Copyright © 2005 by Korean Journal of Medical Mycology

Language

Korean/English

Author

Young Min Shin; Departments of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea
So Hyun Park; Departments of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea
Dong Hoon Shin; Departments of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea
Jong Soo Choi; Departments of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea
Ki Hong Kim; Departments of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea
Young Kyung Bae; Departments of Pathology, College of Medicine, Yeungnam University, Daegu, Korea

Corresponding

Jong Soo Choi, Departments of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea. Tel: (053) 620-3160, Fax: (053) 622-2216, e-mail: jschoi@med.yu.ac.kr

Publication history

Acknowledgements

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Young Min Shin

Departments of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea

So Hyun Park

Departments of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea

Dong Hoon Shin

Departments of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea

Jong Soo Choi

Departments of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea

Ki Hong Kim

Departments of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea

Young Kyung Bae

Departments of Pathology, College of Medicine, Yeungnam University, Daegu, Korea

Since epub date 2016 February 20