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A Case Report of Cutaneous Protothecosis with Severe Pustules and Ulceration

Eun-So Lee,Jie Hoon Kim,Sungnack Lee
Epub 2016 February 23

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Abstract



Protothecosis is unusual phycological disorder caused by algae, named Prototheca. Cutaneous protothecosis has been reported worldwide including Korea. The patient was eighty-eight year old female who complained of skin lesions developed 15 days prior to the first visit. She has been living near the seashore and enjoyed bathing in the sea. Her skin lesions were erythematous, purulent plaque and patch, ulceration on right forearm. Skin biopsy revealed the possibility of cutaneous protothecosis, and this finding was confirmed by histological, mycological and electron microscopical studies. The causative organism was identified as Prototheca wickerhamii. Surgical debridement with KMnO4 wound irrigation combined with intravenous fluconazole 400 mg/day for 3 weeks resulted in remarkable improvement if skin lesions. We report a case of cutaneous protothecosis which showed severe clinical feature and was successfully treated with combination of systemic antifungal agent and surgical debridement.

Keywords


Protothecosis Fluconazole Itraconazole Surgical debridement




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