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A Case of Systemic Fungal Infection due to Fusarium oxysporum in a Patient with Acute Lymphocytic Leukemia

Sung Bin Cho,Jin Wook Lee,Young-Hun Cho,Kwang Hoon Lee
Epub 2016 February 20

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Abstract



Fusariosis is a rare infectious disease caused by species of the genus Fusarium that has been increasingly documented as an emerging agent of opportunistic infections in immunocompromised patients and, occasionally, immunocompetent hosts. We describe an 18-year-old Korean male, previously diagnosed as acute lymphocytic leukemia, presented with 2~4 cm-sized erythematous to necrotic papulonodules on the trunk and extremities for a week. White blood cell count was 200 cells/L and biopsy specimen showed structures resembling fungal elements in the dermis and subcutaneous fat. Cultures from a biopsy sample growing whitish cottony colonies contained fusoid multiseptated macroconidia. He was diagnosed as fusariosis and treated with intravenous amphotericin B. But white

blood cell count and clinical symptoms didn't improve and he was expired after 6 days of treatment.



Keywords


Fusarium oxysporum Acute lymphocytic leukemia




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