Abstract

There is an increasing tendency of systemic fungal infection because of increase in the number of immunocomproised patients such as the patients receiving anticancer chmotherapy or organ transplant. The frequency of systemic fungal infection is problematic, since it is often difficult for clinicians to manage the patients with fungal infection. Amphotericin B was one of the representativ antifungal agent for the systemic antifungal infection even though it has many kinds of advers reactions for instance nephrotoxicity, electrolyte imbalance, etc. Therefore ketoconazole, fluconazole, and itraconazole were develped and prescribed with effect. Because of increase in the number of resistant strains of Candida, Fusarium or Trichosporon nowadays, as for azole antifungal agents there were something to be desired. Other new antifungal agents with fungicidal effect under develpment include polyoxins, echinocandins and pradimicin.

Keywords

Systemic antifungal agents

KJMM 1997 December;2(2):110-122(13). Epub 2016 February 25
Copyright © 1997 by Korean Journal of Medical Mycology

Language

Korean/English

Author

Jun-Hee Woo; Department of Internal Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea
Doo Ryeon Chung; Department of Internal Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea
Jiso Ryu; Department of Internal Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea

Corresponding

Jun-Hee Woo, Department of Internal Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea.

Publication history

Acknowledgements

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Jun-Hee Woo

Department of Internal Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea

Doo Ryeon Chung

Department of Internal Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea

Jiso Ryu

Department of Internal Medicine, University of Ulsan, College of Medicine, Asan Medical Center, Seoul, Korea

Since epub date 2016 February 25